18 January 2009

Dementia linked to diabetes more likely effect of vascular disease

Diabetes associated with different types of brain injury in patients with dementia
JAMA/Archives: 12 January 2009
Patients with dementia and diabetes appear to display a different pattern of injuries in their brains than patients with dementia but without diabetes, according to an article posted online today that will appear in the March print issue of Archives of Neurology, one of the JAMA/Archives journals.

"The association between diabetes mellitus and increased risk for dementia in the elderly is well documented," the authors write as background information in the article. Several possible mechanisms have been proposed for this association, including the direct effects of high blood glucose and insulin, the build-up of beta-amyloid plaques in the brain and the effects of diabetes-related vascular disease on blood vessels in the brain. … > full story : teaching brief

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