27 April 2009

CPHPC drug pilot study encouraging

Drug offers hope on Alzheimer's
Unviersity College London: 15 April 2009
Research led by Professor Mark Pepys FRS (Director of the UCL Centre for Amyloidosis and Acute Phase Proteins) has identified a protein known as serum amyloid P component (SAP) as a possible therapeutic target in Alzheimer’s disease.

In collaboration with pharmaceutical group Roche, Professor Pepys developed a new small molecule drug, CPHPC, which specifically targets SAP and removes it from the blood. New findings, published in the current issue of PNAS and undertaken by Professor Pepys’s team together with Martin Rossor and colleagues from the Dementia Research Centre in the UCL Institute of Neurology, show that the drug also removes SAP from the brains of patients with Alzheimer’s disease.… > full press release: BBC Online story : review by NHS Knowledge Services

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