4 April 2009

Semantic dementia

Effects of disease severity on autobiographical memory in semantic dementia revealed in new study
Elsevier: 2 April 2009
In a study conducted by the Laboratory of Neuropsychology of the Université de Caen Basse-Normandie and published by Elsevier in the April 2009 issue of Cortex), researchers studied for the first time autobiographical memory in a group of semantic dementia (SD) patients according to disease progression. They highlighted that at early stages of the disease those patients could recall recent memories, but also lasting memories from their youth which tend to disappear as dementia evolves. Mechanisms at the root of this autobiographical memory impairment result from storage deficits combined with faulty retrieval strategies.

Semantic dementia is a neurodegenerative disease characterized by a semantic memory breakdown; this type of memory concerns meanings and understandings about the world, e.g. "Paris is the capital of France" as well as personal semantics. Despite their important semantic deficits, these patients show preserved abilities concerning daily living activities and can recall recent specific personal events, with episodic details, at least at the beginning of the disease. This observation is interesting because it suggests that episodic autobiographical memory referring to both recent and old memories, particular to each individual at the source of personal continuity over time, is preserved in early SD. … > full story

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