6 July 2009

A paradigm shift about Alzheimer’s disease

Popular Alzheimer’s theory may be false trail
University of Florida: 15 June 2009
The idea that anti-inflammatory drugs might protect people struggling with dementia from Alzheimer’s disease has received a blow with the online release of a study of human brain tissue in Acta Neuropathologica.

Researchers with the McKnight Brain Institute of the University of Florida, in collaboration with scientists at the University of Frankfurt, Germany, discovered that inflammation of microglia — an abundant cell type that plays an important supporting role in the brain — does not appear to be associated with dementia in Alzheimer’s disease.

The finding supports recent clinical trial results that indicate anti-inflammatory drugs are not effective at fighting dementia in patients with Alzheimer’s disease, which affects about 5.3 million Americans. … > full press release

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