8 August 2009

Cerebrospinal fluid biomarkers predict progression to Alzheimer’s

Biomarkers may help predict risk of Alzheimer disease in patients with mild cognitive impairment
Journal of the American Medical Association: 21 July 2009
Several cerebrospinal fluid (CSF) biomarkers showed good accuracy in identifying patients with mild cognitive impairment who progressed to Alzheimer disease, according to a study in the July 22/29 issue of JAMA.

Alzheimer disease (AD) is the most common cause of dementia, affecting more than 15 million individuals worldwide. Because of the type of progression of the disease, there is a need for methods enabling early diagnosis. "Treatments would need to be initiated very early in the disease process, before the neurodegenerative process is too severe. Much focus has thus been directed on patients with mild cognitive impairment (MCI), which is a syndrome characterized by cognitive impairment beyond the age-adjusted norm, but not severe enough to fulfill the criteria for dementia," the authors write. … > full press release : review by MedPage Today : comments from Mayo Clinic Alzheimer’s disease specialist

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