6 November 2009

Gene predicts risk for Alzheimer’s disease symptoms after traumatic brain injury

Genetic screening tool may determine individual risk of developing amyloid plaques after brain trauma
Penn Medicine: 22 October 2009
The presence of a gene can predict when a traumatic brain injury (TBI) will lead to early symptoms of Alzheimer’s disease, according to a new study from neuroscientists at the University of Pennsylvania School of Medicine. Amyloid plaque deposits, known primarily for their role in Alzheimer’s disease, are found in nearly one third of people who die from acute TBI, within just hours of a brain injury and in people of all ages. This build up of Alzheimer’s-like deposits can be predicted by a variation in the gene that codes for the amyloid-busting enzyme, neprilsyin. … > full press release

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